TRPC6 Cation Channel

A non-selective, calcium permeant TRPC cation channel that contains four ANKYRIN REPEATS and is activated by DIACYLGLYCEROL independently of PROTEIN KINASE C. It is expressed in placenta, lung, spleen, ovary and the small intestine, as well as by PODOCYTES in the kidney glomerulus. Mutations in the TRPC6 gene are associated with FOCAL SEGMENTAL GLOMERULOSCLEROSIS type 2.

Also Known As:

TRPC6; Transient Receptor Potential Cation Channel Subfamily C, Member 6; Cation Channel, TRPC6; Channel, TRPC6 Cation

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - Membrane Transport Proteins: 589
      - Ion Channels: 6731
        Calcium Channels: 3471
        TRPC6 Cation Channel: 509
        Transient Receptor Potential Channels: 706
        TRPC Cation Channels: 6
        TRPC6 Cation Channel: 509
  - Membrane Proteins: 10078
    - Membrane Glycoproteins: 2252
      - Ion Channels: 6731
        Calcium Channels: 3471
        TRPC6 Cation Channel: 509
    - Membrane Transport Proteins: 589
      - Ion Channels: 6731
        Calcium Channels: 3471
        TRPC6 Cation Channel: 509
        Transient Receptor Potential Channels: 706
        TRPC Cation Channels: 6
        TRPC6 Cation Channel: 509

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